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Fatal fulminant hepatitis B after withdrawal of entecavir treatment in a patient with HBeAg seroconversion

Journal Volume 75 - 2012
Issue Fasc.3 - Letters
Author(s) M. Sarikaya, E. Koçak, S. Köklü, A. Babali, B. çakal
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Department of Gastroenterology, Ankara Education and Research Hospital, Ankara, Turkey.

The presence of hepatitis B e antigen (HBeAg) is often associated with ongoing liver disease, whereas HBeAg seroconversion often coincides with loss of serum hepatitis B virus (HBV) DNA, normalization of liver biochemical tests, clinical remission and sub sidence of hepatic inflammatory activity (1). Herein we desribe a patient with HBeAg reversion with acute liver failure after discontinuation of entecavir therapy.

© Acta Gastro-Enterologica Belgica.
PMID 23082714